Posts Tagged ‘effects of cocaine’
What are the long-term effects of cocaine use?
Cocaine is a highly addictive drug. Therefore, it is unlikely that a person can predict or control what or extreme lust will continue using it. It is believed that stimulating and addictive effects of cocaine are primarily the result of its ability to prevent the reabsorption of dopamine by nerve cells. The brain emits dopamine as part of their reward system, and it is directly or indirectly involved in the addictive properties of all major drugs of abuse.
You can develop considerable tolerance to “high” of drugs and many addicts report that, although they try, do not get the same pleasure as when first used. Some users often increase the dosage to intensify and prolong the euphoria. Although tolerance may occur to the “high”, users can also develop more sensitivity (“sensitizer”) to the anesthetic and convulsant effects of cocaine, without having increased the dose. This increased sensitivity may explain why some deaths occurring after use of seemingly small dose of cocaine.
When cocaine is used repeatedly and in increasing doses, can lead to a state of irritability, restlessness and paranoia. This can cause a total paranoid psychosis episode in which a person loses touch with reality and suffers from hallucinations.
Ready vaccine for cocaine addiction
Scientists in California have discovered a vaccine that neutralizes cocaine addiction in mice, and now prepare a human version could also work with other addictive as nicotine and methamphetamine.
“Our very dramatic results show that we can protect mice from the effects (addictive) of cocaine, and we believe these ranges are very promising in the fight against addiction in humans,” said the director of research, Ronald Crystal.
The project Scripps Research Institute in La Jolla, says the vaccine creates antibodies that neutralize the effects of cocaine that create addiction.
A co-researcher, Kim Jandra, said the vaccine “deleted the stimulant effects of cocaine.”
He emphasized that the vaccine blocks the effects of cocaine before it reaches the brain.
In the laboratory model, the vaccine provided immunity to mice for a period of 13 weeks. Read the rest of this entry »
Effects of cocaine
Cocaine is a very powerful drug, capable of significantly altering the psychophysiological state of the consumer. Throughout the history of coca has been used as an invigorating fitness. The ability of cocaine to reduce hunger and fatigue and stimulate muscle activity has been widely recognized. It has been suggested that this effect is due to the consequent increase in blood acidity, from uric acid, and stimulation of the degradation of carbohydrates for energy in the tissues. Even assuming that this metabolic action occurs, the effect on the consumer still depends on many factors. As with any drug, the effects of a minimum dose vary with the particular mental and physical well-being of consumers.
Stimulation is much deeper if the individual is below normal, you feel tired or hungry. The effects are minimal if present the normal euphoria associated with good health. Cocaine has been shown to have a positive effect on muscle activity in general and, more specifically, reaction time and muscle strength.
Researchers have been unable to demonstrate any direct effect of cocaine on motor nerves or muscle groups, hence, have concluded that their effect is probably indirect, acting to increase the overall sense of well-being and willingness to work .
Pharmacologically, cocaine produces two different and unrelated actions: Read the rest of this entry »
Cocaine brain effects
Cocaine is a substance with a strong stimulant that acts directly on the central nervous system. There, the cocaine is focused on certain neurotransmitters such as dopamine, which regulates the pleasure centers and movement. On dopamine, cocaine does nothing to increase the amounts generated in this neurotransmitter.
Dopamine is a chemical that is issued by the Cerberus as a response or reaction to an incentive pleasant. As the mobile dopamine which communicated some of the cells of the brain, when there is such an incentive fought dopamine cells, which returns to its original cell when the stimulus stops, cutting off communication between neurons.
With cocaine, what happens is that it somehow prevents the return of dopamine to its cell of origin. That is, after the stimulation caused by drugs, dopamine issued not return to its starting place, so it does not break the communication between cells, causes a buildup of dopamine. Read the rest of this entry »
Cocaine
In cocaine use, there are several contingencies that alter the potential impact that this occurs in individuals who consume it. The different ways that produce different effects on consumers, lie in the way you use drugs, in the amount of substance to be consumed in the reception of the consumer, and, above all, the quality of the substance, which is directly linked to the substance which has been mixed.
When consumed, cocaine produces an immediate effect on the consumer. It highlights the euphoria that generates excitement and confidence. Promotes loss of appetite and sleep and energy. The disappearance of these primary effects, comes another stage in the process of cocaine, leading other states, which are linked to the characteristics mentioned above, such as the amount is consumed, the quality of the substance and the frequency with which they do .
The normal state between those who use cocaine regularly, is a decline in mood, accentuated by a deep depression. These bodies are those that are generating the need to use again, usually by simply avoiding that feeling. Read the rest of this entry »